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4-1BB

4-1BB

Our Immune Checkpoint Partners

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  • Bio X Cell
  • ACRO Biosystems
  • Arigo Bio
  • OriGene

4-1BB, also known as CD137, belongs to the TNF-receptor superfamily. It is expressed by T-cells and, upon binding to the 4-1BB ligand (known as 4-1BBL or CD137L) on antigen presenting cells, promotes T-cell proliferation and survival. Since the 4-1BB ligand is expressed by various carcinoma cells, blocking the interaction between 4-1BB and 4-1BBL is investigated as a means of treating cancer. 4-1BB is also studied by researchers investigating autoimmune diseases such as collagen-induced arthritis (CIA), multiple sclerosis and systemic lupus erythematosus (SLE).

4-1BB related antibodies from preferred suppliers:

Below are more purified version:

for more information on the differences between InVivoMAb and InVivoPlus please click HERE!

4-1BB related proteins from preferred suppliers:

4-1BB related conjugated proteins:

4-1BB related ELISA kits from preferred suppliers:

  • ARG81801 - Human CD137 ELISA Kit - is an Enzyme immunoassay kit for the quantification of human CD137 in serum, plasma (heparin, EDTA) and cell culture supernatants.
  • ARG81820 - Mouse CD137 ELISA Kit -  is an Enzyme immunoassay kit for the quantification of mouse CD137 in serum, plasma (heparin, EDTA) and cell culture supernatants.

4-1BB related Cell Lines from preferred supplier:

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