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Pooled CRISPRi Libraries

The engineering of deactivated Cas9 (dCas9) has shown to be an effective modulator of gene expression  when complexed with proteins that repress (e.g., KRAB) or activate (e.g., VPH) gene targets and delivered directly to upstream promoter regions of genes. CRISPR interference, also known as CRISPRi, uses this technology as its foundation. Through CRISPR interference (CRISPRi), one can target specific promoters within genes to perform genetic screens for isoform-specific loss-of-function mutations

Product Catalog

Catalog No. Description
KIHGW-106-P Human Genome-Wide CRISPRi sgRNA Library (plasmid)
KIHGW-106-V8 Human Genome-Wide CRISPRi sgRNA Library (virus)
KIHGW-106-V9 Human Genome-Wide CRISPRi sgRNA Library (virus)
KIDHGW-105K-P Human Genome-Wide CRISPRi Dual-sgRNA Library (plasmid)
KIDHGW-105K-V8 Human Genome-Wide CRISPRi Dual-sgRNA Library (virus)
KIDHGW-105K-V9 Human Genome-Wide CRISPRi Dual-sgRNA Library (virus)
KIMGW-109-P Mouse Genome-Wide CRISPRi sgRNA Library (plasmid)
KIMGW-109-V8 Mouse Genome-Wide CRISPRi sgRNA Library (virus)
KIMGW-109-V9 Mouse Genome-Wide CRISPRi sgRNA Library (virus)

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