ALK Antibody (pTyr1507) Product Size(s) 100 ul £448.00 SPC-913D Add to order Added to order Academic Pricing Please contact us for academic pricing. Contact Us About this Product SKU: SPC-913D Additional Names: Alk Antibody, Anaplastic lymphoma kinase Antibody, CD246 Antibody, NBLST3 Antibody Application: Antibody Microarray, Western Blot CE/IVD: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only. Clonality: Polyclonal Extra Details: ALK is a receptor-tyrosine kinase (belonging to the insulin receptor family) that is activated upon binding an unidentified ligand. Chromosomal rearrangments (most common), mutations, and amplifications in this gene are associated with numerous tumours including: anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. These fusion proteins, as well as other mutations and amplifications, likely confer hightened (possibly consititutive) kinase activity and thus promote cell growth and anti-apoptotic pathways such as the Akt MAPK pathways. Gene Details: ALK Host: Rabbit Immunogen: A phospho-specific peptide corresponding to residues surrounding Tyr1507 of human ALK (AA1504-1510) Protein Details: Q9UM73 Purification: Affinity Purified Reactivities: Human Shipping Conditions: Blue Ice Storage Conditions: -20[o]C Supplier: StressMarq Biosciences Type: Antibody: Polyclonal Antibody Size: 100 ul Manufacturer's Data Sheet: Accession: NP_004295 Need Help?