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Cyclic GMP CLIA Kit (High-Sensitivity)

SKU:
SKT-210-96
Academic Pricing:
Please contact us at info@2bscientific.com for specific academic pricing
Additional Names:
cGMP; 3',5'-cyclic GMP CLIA Kit, Guanosine cyclic monophosphate CLIA Kit, Cyclic 3',5'-GMP; Guanosine 3',5'-cyclic phosphate CLIA Kit
CE/IVD:
IVD
Extra Details:
Guanosine 3', 5'-cyclic monophosphate (cyclic GMP; cGMP) is a critical and multifunctional second messenger present at levels typically 10-100 fold lower than cAMP in most tissues. Intracellular cGMP is formed by the action of the enzyme guanylate cyclase on GTP and degraded through phosphodiesterase hydrolysis (1-3). Guanylate cyclases (GC) are either soluble or membrane bound (3,4). Soluble GCs are nitric oxide responsive, whereas membrane bound GCs respond to hormones such as acetylcholine, insulin and oxytocin. Other chemicals like serotonin and histamine also cause an increase in cGMP levels (5,6). Cyclic GMP regulates cellular composition through cGMP-dependent kinase, cGMP-dependent ion channels or transporters, and through its hydrolytic degradation by phosphodiesterase (1,7)
Range:
Regular: 0.0469 - 3 pmol/ml. Acetylated: 0.03125 - 1 pmol/ml
Sensitivity:
0.034 pmol/ml
Shipping Conditions:
Blue Ice
Storage Conditions:
4oC
Supplier:
StressMarq Biosciences Inc
Size:
96 well
  • Download:
Price for 96 well £546.00

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