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Assay Kits & ELISAs

E3LITE Customizable Ubiquitin Ligase Kit

Product Sizes
E3LITE Customizable Ubiquitin Ligase Kit
£1,787.00
UC-0101-A384
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
UC-0101-A384
Extra Details:
The E3LITE Customizable Ubiquitin Ligase Kit is a robust assay that allows for the quantification of the E3 ubiquitin ligase activity. The kit uses a plate that is pre-coated with a proprietary polyubiquitin capture reagent. The resulting product of the E3 ligase-mediated in vitro ubiquitin reaction is measured and represents a direct measure of the E3 ligase activity. The E3LITE Customizable Ubiquitin Ligase Kit represents a singular platform for the focused investigation of any E2/E3 enzyme pair, as well as any particular polyubiquitin linkage type. This assay has been validated for high throughput screening (HTS) and has been employed in the discovery of novel compounds that selectively modulate E3 ligase function. \nKit Components \n-- Ubiquitin E1 Activating Enzyme \n-- Choice of Ubiquitin E2 Conjugating Enzyme(s) \n-- E1-E2-E3 Control \n-- Choice of Recombinant Ubiquitin \n-- Detection Reagent 1 \n-- Linear Polyubiquitin Control \n-- (2) modular 96- or 384-well pre-coated plates
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C
Size:
2 plates
Supplier:
LifeSensors
Type:
Assay Kits: Detection