17-AAG
Product Sizes
17-AAG
£172.00
AC-2005-0001
About this Product
- SKU:
- AC-2005-0001
- Application:
- Cell-based/Functional Assay
- CAS Number:
- 75747-14-7
- Extra Details:
- Tanespimycin (17-AAG) is a cell permeable, less toxic and more stable semi-synthetic analog of geldanamycin. 17-AAG is a potent HSP90 inhibitor displaying a 100-fold higher affinity for tumor cell derived HSP90 over normal cell HSP90. 17-AAG displays anti-angiogenic activity and sensitizes tumor cells to apoptosis in response to such agents as taxol and cisplatin. Tanespimycin (17-AAG) depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin (17-AAG) also downregulates stk38 gene expression.
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- 2-8[o]C
- Size:
- 1 mg
- Supplier:
- LifeSensors
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
- Manufacturer's Data Sheet:https://lifesensors.com/product/ac2005-17-aag/