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Antibodies

Anti USP2core Antibody

Product Sizes
Anti USP2core Antibody
£543.00
AB-0501-0250
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
AB-0501-0250
Additional Names:
41 kDa ubiquitin-specific protease;deubiquitinating enzyme 2;ubiquitin carboxyl-terminal hydrolase 2;ubiquitin specific protease 12;ubiquitin specific protease 9;ubiquitin thioesterase 2;ubiquitin-specific-processing protease 2;UBP41;USP9
Application:
Western Blot
Extra Details:
USP2 core represents the common catalytic core domain of the two isoforms of USP2, USP2a and USP2b. In vitro studies revealed that the USP2 core was able to deubiquitylate high molecular weight proteins from testis extracts and cleave Ub-PLA2 with efficiently. USP2a is androgen-regulated, overexpressed in prostate tumors and has been reported to serve an anti-apoptotic function in prostate cancer. Furthermore, ectopic expression of USP2a in non-transformed cells promotes oncogenic behavior in vitro and in vivo. Notably, Priolo et al also demonstrated that the E3 ubiquitin ligase Hdm2 was deubiquitylated by USP2a.
Gene Details:
USP2
Host:
Chicken/Avian
Protein Details:
O75604
Reactivities:
Human
Shipping Conditions:
Dry Ice
Storage Conditions:
-20[o]C
Size:
250 ug
Supplier:
LifeSensors
Type:
Antibody