AY-NH2
About this Product
- SKU:
- PR-020
- Additional Names:
- AYPGKF-NH2
- CAS Number:
- 352017-71-1
- Extra Details:
- AY-NH2, also known as AYPGKF-NH2, is a selective PAR4 receptor agonist peptide. AY-NH2 stimulates platelet aggregation in vitro with an EC50 of 15 μM and can cause an increase in paw thickness in the paw edema inflammation model.
- Molecular Weight:
- 680.8
- Purity:
- >95% by hplc
- References:
- <p>Faruqi et al (2000) Structure-function analysis of protease-activated receptor 4 tethered ligand peptides. J.Biol.Chem. <strong>275</strong> 19728 <a href="https://pubmed.ncbi.nlm.nih.gov/10779527/" target="_blank" rel="nofollow">PMID: 10779527</a></p><p>Palygin et al (2016), Protease-activated Receptor-1-driven Intracellular Calcium Dynamics in Rat Glomerular Podocytes. FASEB J. <strong>30</strong> 968.25 <a href="https://pubmed.ncbi.nlm.nih.gov/27733370/" target="_blank" rel="nofollow">PMID: 27733370</a></p><p>Meyer et al (2020) Platelet Interactions with Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells Lead to Hepatocyte Proliferation. Cells <strong>9</strong>(5) 1243 <a href="https://pubmed.ncbi.nlm.nih.gov/32443494/" target="_blank" rel="nofollow">PMID: 32443494</a></p>
- Sequence:
- H-Ala-Tyr-Pro-Gly-Lys-Phe-NH2
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble to 2 mg/ml in water
- Formula:
- C34H48N8O7