Angiotensin (1-7)
Product Sizes
Angiotensin (1-7)
£87.00
NR-160
About this Product
- SKU:
- NR-160
- CAS Number:
- 51833-78-4
- Extra Details:
- Angiotensin (1-7) is an endogenous peptide fragment and key component of the renin-angiotensin system (RAS). It is created from the conversion of angiotensin II (Ang II) into angiotensin (1-7) by angiotensin converting enzyme 2 (ACE2) and acts through activation of the non-AT1, non-AT2 receptor Mas. There are numerous examples of the effects of angiotensin (1-7) in the cardiovascular system where it counteracts the vasoconstrictive and proliferative effects of angiotensin II and also stimulates vasopressin release in vivo.
- Molecular Weight:
- 899
- Purity:
- >95% by HPLC
- References:
- <p>Santos et al (2003) Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc.Natl.Acad.Sci.U.S.A. <strong>100</strong> 8258 <a href="https://pubmed.ncbi.nlm.nih.gov/12829792/" target="_blank" rel="nofollow">PMID: 12829792</a></p><p>Santos (2014) Angiotensin-(1-7) Hypertension<strong> 63</strong>(6) 1138 <a href="https://pubmed.ncbi.nlm.nih.gov/24664288/" target="_blank" rel="nofollow">PMID: 24664288</a></p><p>Patel et al (2016) Role of the ACE2/Angiotensin 1-7 Axis of the Renin-Angiotensin System in Heart Failure. Circulation Res. <strong>118</strong>(8) 1313 <a href="https://pubmed.ncbi.nlm.nih.gov/27081112/" target="_blank" rel="nofollow">PMID: 27081112</a></p>
- Sequence:
- H-Asp-Arg-Val-Tyr-Ile-His-Pro-OH
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store frozen, dark and desiccated
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in dilute acid
- Formula:
- C41H62N12O11