Akt substrate
Product Sizes
Akt substrate
£94.00
KS-040
About this Product
- SKU:
- KS-040
- Additional Names:
- Akt/SKG substrate peptide
- CAS Number:
- 276680-69-4
- Extra Details:
- Akt substrate peptide, also known as Akt/SKG substrate peptide, is a 7 amino acid synthetic peptide suitable as a substrate for Akt, also known as protein kinase B (PKB), the serine/threonine-specific protein kinase that plays a key role in multiple cellular processes such as glucose metabolism, apoptosis, cell proliferation, transcription, and cell migration. Unlike other substrates, Akt substrate peptide is not phosphorylated by p70 S6 kinase or MAP kinase activated protein (MAPKAP) kinase-1.
- Molecular Weight:
- 817.9
- Purity:
- >95% by HPLC
- References:
- <p>Alessi et al (1996) Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett.<strong> 399</strong> 333 PMID: 8985174</p><p> Cutillas et al (2006) Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase / Akt signal transduction pathway by mass spectrometry. Proc.Natl.Acad.Sci.U.S.A. <strong>103</strong> 8959 PMID: 16751276</p>
- Sequence:
- H-Arg-Pro-Arg-Ala-Ala-Thr-Phe-OH
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in dilute acid
- Formula:
- C36H59N13O9