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Proteins and Peptides

<p>α-Calcitonin gene related peptide (human) <br></p>

Product Sizes
<p>α-Calcitonin gene related peptide (human) <br></p>
£294.00
CG-010
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
CG-010
Additional Names:
α-CGRP (human)
CAS Number:
90954-53-3
Extra Details:
α-Calcitonin gene related peptide (human) is a potent, long-lasting vasodilator which possesses protective mechanisms for physiological and pathological conditions involving the cardiovascular system and wound healing. CGRP is primarily released from sensory nerves and can function in the transmission of nociception.  α-Calcitonin gene related peptide (human) acts as an appetite suppressant and contributes to gastric acid secretion.
Molecular Weight:
3789.33
Purity:
>95% by hplc
References:
<p>Brain et al (1985) Calcitonin gene-related peptide is a potent vasodilator. Nature <strong>313</strong> 54 <a href="https://pubmed.ncbi.nlm.nih.gov/3917554/" target="_blank" rel="nofollow">PMID: 3917554</a></p><p>Poyner et al (2002) International union of pharmacology XXXII. The mammalian calcitonin gene-related peptides, adrenomedullin, amylin, and calcitonin receptors. Pharmacol.Revs. <strong>54</strong> 233 <a href="https://pubmed.ncbi.nlm.nih.gov/12037140/" target="_blank" rel="nofollow">PMID: 12037140</a></p><p>Russell et al (2014) Calcitonin gene-related peptide: physiology and pathophysiology. Physiol Rev.<strong> 94</strong>(4) 1099 <a href="https://pubmed.ncbi.nlm.nih.gov/25287861/" target="_blank" rel="nofollow">PMID: 25287861</a></p>
Sequence:
H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2, disulfide bridge between cysteines 2 and 7
Shipping Conditions:
Ambient
Storage Conditions:
Store dessicated, frozen and in the dark
Size:
1 mg
Supplier:
Isca Biochemicals
Solubility:
Soluble to 0.50 mg/ml in water
Formula:
C163H267N51O49S2