H-151 Product Size(s) £142.00 10-4132-10mg Add to order Added to order Academic Pricing Please contact us for academic pricing. Contact Us About this Product SKU: 10-4132-10mg CAS Number: 941987-60-6 Extra Details: H-151 is an inhibitor of the signaling molecule STING in mouse and human cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. It reduced systemic cytokine response in mice treated with the STING agonist 10-carboxymethyl-9-acridanone and showed efficacy in Trex-/- mice. Molecular Weight: 279.34 Physical State: Off-white solid References: 1) Haag et al. (2018), Targeting STING with covalent small-molecule Inhibitors; Nature 559 269 Shipping Conditions: Ambient Storage Conditions: -20°C Supplier: Focus Biomolecules Manufacturer's Data Sheet: Purity: 98%, NMR (Conforms) Chemical Name: N-(4-Ethylphenyl)-N’-1H-indol-3-yl urea Need Help?