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Recombinant Clostridium tetani Tetanus Toxin Light Chain (Active)

SKU:
P202001-10
Additional Names:
TeNT-LC, Tetanus Neurotoxin Light Chain, Tetanospasmin Light Chain, Spasmogenic Toxin Light Chain, TetX Light Chain
Buffer:
Supplied as a 0.22 µm filter sterilised solution in 50mM Tris, 0.05% Tween-20, 2% glycerol, pH 7.4
Extra Details:
Biological Activity: >50% of substrate is cleaved by 40 ng, as measured by the cleavage of the substrate Human VAMP2 in a gel-shift assay
Host:
Clostridia
Molecular Weight:
56.9 kDa
Protein Details:
2-457aa, N-terminal Clostridial signal peptide, C-terminal 6-His tag
Purity:
>90% by SDS-PAGE under reducing conditions visualised by Coomassie stain; Endotoxin Level <0.005 EU/ug by the LAL method
Sequence:
PITINNFRYS DPVNNDTIIM MEPPYCKGLD IYYKAFKITD RIWIVPERYE FGTKPEDFNP PSSLIEGASE YYDPNYLRTD SDKDRFLQTM VKLFNRIKNN VAGEALLDKI INAIPYLGNS YSLLDKFDTN SNSVSFNLLE QDPSGATTKS AMLTNLIIFG PGPVLNKNEV RGIVLRVDNK NYFPCRDGFG SIMQMAFCPE YVPTFDNVIE NITSLTIGKS KYFQDPALLL MHELIHVLHG LYGMQVSSHE IIPSKQEIYM QHTYPISAEE LFTFGGQDAN LISIDIKNDL YEKTLNDYKA IANKLSQVTS CNDPNIDIDS YKQIYQQKYQ FDKDSNGQYI VNEDKFQILY NSIMYGFTEI ELGKKFNIKT RLSYFSMNHD PVKIPNLLDD TIYNDTEGFN IESKDLKSEY KGQNMRVNTN AFRNVDGSGL VSKLIGLCKK IIPPTNIREN LYNRTA
Shipping Conditions:
Blue Ice
Source:
Clostridium tetani
Storage Conditions:
Repeated freeze-thaw cycles are not recommended. Store at -20 to -80 °C
Supplier:
Biocleave
Type:
PB
Size:
10 ug
  • Manufacturer's Data Sheet:
Price for 10 ug £300.00

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