Skip to content

Basket

You currently have no items in your basket.

InVivoPlus anti-mouse CD40, clone - FGK4.5/FGK45, IgG2a

SKU:
BP0016-2-25MG
Academic Pricing:
Please contact us at info@2bscientific.com for specific academic pricing
Application:
In Vitro Studies, In Vivo Studies
Buffer:
IP0070
Clone:
FGK4.5/FGK45
Clonality:
Monoclonal
Concentration:
Lot specific,typically between 2-10 mg/ml
Extra Details:
Recommended Isotype Control - BP0089; CD40 is a 48 kDa type I transmembrane glycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD40 is expressed broadly on antigen-presenting cells (APCs) such as dendritic cells, B cells, macrophages, and monocytes as well as non-immune endothelial cells, basal epithelial cells, and a range of tumors. Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. Agonistic CD40 monoclonal antibodies have been shown to activate APCs and promote anti-tumor T cell responses. The FGK4.5 antibody is an agonistic antibody that has been shown to activate CD40 expressing APCs. FGK4.5 can also be used to inhibit CD40/CD154 interaction in vitro and in vivo.
Host:
Rat
Immunogen:
CD40
Isotype:
IgG2a
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
BioXCell
  • Download:
Price £1871.00

We use cookies to give you the best experience of using this website. By continuing to use this site, you accept our use of cookies. Please read our Cookie Policy for more information.