Human CD172a / SIRP alpha recombinant protein (ECD) (Fc-His-tagged, C-ter)
Product Sizes
100 ug
£764.00
ARG70267-100UG
About this Product
- SKU:
- ARG70267
- Additional Names:
- CD172A; p84; SHPS1; SHPS-1; CD172 antigen-like family member A; Sirp-alpha-3; Sirp-alpha-1; BIT; MYD-1; MFR; Bit; PTPNS1; CD antigen CD172a; Inhibitory receptor SHPS-1; SIRP; MyD-1 antigen; Sirp-alpha-2; Tyrosine-protein phosphatase non-receptor type substrate 1; Signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; Macrophage fusion receptor; Brain Ig-like molecule with tyrosine-based activation motifs; P84; SHP substrate 1
- Application:
- Cell-based/Functional Assay, SDS-PAGE
- Buffer:
- PBS (pH 7.4)
- CE/IVD:
- RUO
- Extra Details:
- The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene. [provided by RefSeq, Jul 2008]
- Purity:
- >95%
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C
- Supplier:
- Arigo Biolaboratories
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Recombinant Proteins
