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anti-HMGB1 Neutralizing antibody [SQab20175] (low endotoxin)

SKU:
ARG66714-100UG
Additional Names:
HMG-1; High mobility group protein B1; High mobility group protein 1; HMG1; SBP-1; HMG3
Application:
Block/Inhibit/Neutralise, ELISA, Flow Cytometry, Western Blot
Buffer:
PBS (pH 7.4)
CE/IVD:
For laboratory research only, not for drug, diagnostic or other use.
Clone:
SQab20175
Clonality:
Monoclonal
Concentration:
1 mg/ml
Extra Details:
HMGB1 is a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2015]
Gene Details:
HMGB1
Host:
Mouse
Immunogen:
Human HMGB1.
Isotype:
IgM, kappa
Protein Details:
P09429
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
2[o]C to 8[o]C or -20[o]C
Supplier:
Arigo Bio
Type:
Antibody: Monoclonal Antibody
Size:
100 ug
Specificity:
This antibody could specifically neutralize HMGB1 induced pathway but not HMGB2 tested by TNF alpha releasing assay.
Synonyms:
Amphoterin;High mobility group protein 1;high mobility group protein B1;high-mobility group (nonhistone chromosomal) protein 1;HMG1;HMG-1;HMG3;SBP-1;Sulfoglucuronyl carbohydrate binding protein
Price for 100 ug £598.00

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