anti-CD284 / TLR4 antibody SKU: ARG58766-100UL Additional Names: CD284; CD antigen CD284; ARMD10; hToll; TLR-4; TOLL; Toll-like receptor 4 Application: IHC-Paraffin, Immunocytochemistry, Immunofluorescence Buffer: PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. CE/IVD: For laboratory research only, not for drug, diagnostic or other use. Clonality: Polyclonal Extra Details: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Gene Details: TLR4 Host: Rabbit Immunogen: Synthetic peptide within aa. 500-600 of Human TLR4 (NP_612564.1). Isotype: IgG Protein Details: O00206 Purification: Affinity Purified Shipping Conditions: Blue Ice Storage Conditions: -20[o]C Supplier: Arigo Bio Type: Antibody: Polyclonal Antibody Size: 100 ul Manufacturer's Data Sheet:ARG58766.html Preservative: 0.02% Sodium azide Synonyms: ARMD10;CD284;homolog of Drosophila toll;hToll;TLR-4;TOLL;toll like receptor 4 protein;toll-like receptor 4 Immunofluorescence: HeLa cells stained with ARG58766 anti-CD284 / TLR4 antibody at 1:100 dilution. Immunohistochemistry: Paraffin-embedded Mouse slpeen stained with ARG58766 anti-CD284 / TLR4 antibody at 1:100 dilution. Price for 100 ul £529.00 Qty: Add to order Hi, 2B Team here, how can we make a difference? Chat Academic Pricing Please contact us for academic pricing. Contact Us