anti-CD284 / TLR4 antibody SKU: ARG54702-100UL Additional Names: CD284; CD antigen CD284; ARMD10; hToll; TLR-4; TOLL; Toll-like receptor 4 Application: Flow Cytometry, Western Blot Buffer: PBS and 0.09% (W/V) Sodium azide CE/IVD: For laboratory research only, not for drug, diagnostic or other use. Clonality: Polyclonal Extra Details: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Gene Details: TLR4 Host: Rabbit Immunogen: KLH-conjugated synthetic peptide corresponding to aa. 669-698 (Center) of Human TLR4 (NP_003257.1). Protein Details: O00206 Purification: Protein A Purified Reactivities: Bovine, Hamster, Porcine Shipping Conditions: Blue Ice Storage Conditions: -20[o]C Supplier: Arigo Bio Type: Antibody: Polyclonal Antibody Size: 100 ul Manufacturer's Data Sheet:ARG54702.html Preservative: 0.09% Sodium azide Accession: NP_003257.1 Synonyms: ARMD10;CD284;homolog of Drosophila toll;hToll;TLR-4;TOLL;toll like receptor 4 protein;toll-like receptor 4 Flow Cytometry: U251 cells stained with ARG54702 anti-CD284 / TLR4 antibody (right histogram) or without primary antibody control (left histogram). Western blot: 30 µg of Jurkat, K562, PC3, HepG2, Raw264.7, NIH3T3, Mouse liver, Mouse ovary, Rat liver and Rat ovary lysates stained with ARG54702 anti-CD284 / TLR4 antibody at 1:500 dilution. Price for 100 ul £515.00 Qty: Add to order Hi, 2B Team here, how can we make a difference? Chat Academic Pricing Please contact us for academic pricing. Contact Us