anti-CD284 / TLR4 antibody [HTA125] Citation Available Product Size(s) 100 ug £587.00 ARG22986-100UG Add to order Added to order Academic Pricing Please contact us for academic pricing. Contact Us About this Product SKU: ARG22986-100UG Additional Names: CD284; CD antigen CD284; ARMD10; hToll; TLR-4; TOLL; Toll-like receptor 4 Application: Flow Cytometry, Immunoprecipitation, Mass Cytometry, Western Blot Buffer: PBS and 0.09% Sodium azide CE/IVD: RUO Clone: HTA125 Clonality: Monoclonal Concentration: 1 mg/ml Extra Details: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Gene Details: TLR4 Host: Mouse Immunogen: Ba/F3 cell line expressing TLR4 (CD284). Isotype: IgG2a Protein Details: O00206 Purification: Protein G Purified Shipping Conditions: Blue Ice Storage Conditions: -20[o]C Supplier: Arigo Bio Type: Antibody: Monoclonal Antibody Size: 100 ug Need Help? View product citations for antibody ARG22986-100UG on CiteAb