anti-CD284 / TLR4 antibody [HTA125] (Biotin) SKU: ARG22983-50UG Additional Names: CD284; CD antigen CD284; ARMD10; hToll; TLR-4; TOLL; Toll-like receptor 4 Application: Flow Cytometry Buffer: PBS, 0.09% Sodium azide and 1% BSA CE/IVD: For laboratory research only, not for drug, diagnostic or other use. Clone: HTA125 Clonality: Monoclonal Conjugate: Biotin Concentration: 0.1 mg/ml Extra Details: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Gene Details: TLR4 Host: Mouse Immunogen: Ba/F3 cell line expressing TLR4 (CD284). Isotype: IgG2a Protein Details: O00206 Purification: Protein G Purified Shipping Conditions: Blue Ice Storage Conditions: 2-8[o]C Supplier: Arigo Bio Type: Antibody: Monoclonal Antibody Size: 50 ug Manufacturer's Data Sheet:ARG22983.html Preservative: 0.09% Sodium azide Synonyms: ARMD10;CD284;homolog of Drosophila toll;hToll;TLR-4;TOLL;toll like receptor 4 protein;toll-like receptor 4 Price for 50 ug £509.00 Qty: Add to order Hi, 2B Team here, how can we make a difference? Chat Academic Pricing Please contact us for academic pricing. Contact Us