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Human Integrin isoform alpha-7X2B beta 1 (ITGA7X2B&ITGB1) Heterodimer Protein, His Tag&Tag Free

SKU:
IT1-H52W8-1MG
Additional Names:
Integrin isoform alpha-7X2B beta 1|ITGA7X2B&ITGB1|ITGA7X2BB1
Buffer:
50 mM Tris, 150 mM NaCl, pH7.5
Extra Details:
Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers, which is highly expressed in cardiac muscle, skeletal muscle and smooth muscle cells, and localizes to Z-disc and costamere structures. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). ITGA7 has been shown to interact with Merosin, ITGB1, FHL2 and FHL3.
Molecular Weight:
116.5 kDa (ITGA7X2B) & 83.7 kDa (ITGB1)
Physical State:
Powder
Purity:
>90%
Shipping Conditions:
Ambient
Storage Conditions:
-20[o]C
Supplier:
ACRO Biosystems
Type:
Proteins, Peptides, Small Molecoles & Other Biomolecules: Recombinant Proteins
Size:
5 x 200 ug
Accession:
NP_002197.2
Price for 5 x 200 ug £2873.00

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