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ACE2, receptor of 2019-nCoV

Arigo offers IP-grade AEC2 antibody (ARG41099) that is excellent for studying the interaction of SARS-CoV-2 and ACE2 and the vital infection. Moreover, a series of antibodies and ELISA kit are available to facilitate coronavirus research.

The novel coronavirus (SARS-CoV-2) which caused an epidemic of acute respiratory syndrome shares 79.5% sequence identify to SARS-CoV. Recently, several reports indicated that SARS-CoV-2 and SARS-CoV share the same receptor ACE2 for mediating viral entry into host cells.

ACE2 (angiotensin-converting enzyme-2) is previously known as the receptor for SARS-CoV. Based on structural analysis, Wan et al., and Xu et al., point that ACE2 could be the receptor for SARS-CoV-2. Zhou et al., conducted virus infectivity studies and confirmed that ACE2 is required for entry of 2019-nCoV into HeLa cells. More understanding about the interaction of SARS-CoV-2 and ACE2 can lead to anti-infective strategies such as ACE2 protein blockade or neutralizing antibodies.

ACE2 antibody & ELISA kit

ACE2 antibody (ARG41099)

  • Reactivity: Hu, Ms, Rat
  • Application: IHC-P, IP, WB

Human ACE2 ELISA Kit (ARG80959)

  • Sensitivity: 12.5 pg/ml
  • Sample: Serum, plasma, lysate, cell culture supernatant

Coronavirus antibodies & ELISA kits

  • Coronavirus antibody [5A4] (ARG10284)
  • SARS-CoV Sm antibody (ARG54885)
  • SARS-CoV s Sn antibody (ARG54886)
  • SARS -CoV PUPM antibody (ARG54884)
  • MERS-CoV Nucleocapsid antibody (ARG10987)
  • Anti-Canine Coronavirus IgG ELISA Kit (ARG80985)
  • Anti-Feline Coronavirus antibody ELISA Kit (ARG81004)
  • Feline Coronavirus antibody (ARG22654)

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