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Custom Genetic Screening

CRISPR and RNAi Genetic Screening Services
Custom Pooled Lentiviral Libraries
Engineered Custom Cell Lines
DriverMapTM Expression Profiling Service
Individual Lentiviral Custom Constructs
Lentiviral Packaging Services
Next-Generation Sequencing of Samples from High-Throughput Genetic Screens

Based in the North American Pacific Coast, our highly experienced and skilful partnering labs focus on developing and implementing flexible and scalable broad-based approaches for screening and analysis to expedite the discovery and characterisation of novel therapeutic targets and drugs. With strong links and highly suportive of research oriented institutes, they have amassed experience and technical expertise with CRISPR, RNAi, lentiviral vector systems, mammalian cell culture, next generation sequencing (NGS), RT-PCR and gene expression analysis.

To enable investigators to leverage their knowledge, proficiency, and capabilities to advance their research programs, they offer a range of services, including genome-wide functional genetic screens using pooled RNAi and CRISPR libraries, transriptome profiling, cell engineering, and targeted knockdown and knockout constructs.

  • CRISPR and RNAi Genetic Screening Services - using the CRISPR/Cas9 system for screening. Start by using either the pooled CRISPR Human Genome Knockout Library or a Custom Pooled sgRNA Library targeting your own set of genes. After transducing cells with Cas9 and selecting cells expressing a high level of Cas9, the cells are transduced with the sgRNA library and the screen is performed. Cellecta Inc. have developed effective, scalable, high-throughput CRISPR screening services, and all steps can be performed for comprehensive CRISPR screens with your cell models. Email us for more information at Info@2BScientific.com​
  • Custom Pooled Lentiviral Libraries - for the variety of services offered please email us for more information at Info@2BScientific.com
  • Engineered Custom Cell Lines - for the variety of services offered please email us for more information at Info@2BScientific.com
  • DriverMapTM Expression Profiling Service - for the variety of services offered please email us for more information at Info@2BScientific.com
  • Individual Lentiviral Custom Constructs - for the variety of services offered please email us for more information at Info@2BScientific.com
  • Lentiviral Packaging Services - for the variety of services offered please email us for more informationat Info@2BScientific.com
  • Next-Generation Sequencing of Samples from High-Throughput Genetic Screens - for the variety of services offered please email us for more information at Info@2BScientific.com

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