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Visikol Inc is a New Jersey-based biotech company focused on developing bio-imaging tools that allow researchers to obtain a more complete and accurate picture of biological tissues. The company is focused on solving a fundamental problem in the life sciences which is that researchers characterize tissues such as mouse brains using a four-hundred-year-old two-dimensional histological approach that is limited in describing the characteristics of three-dimensional biology. To solve this problem, the Visikol team has invented a patented tissue clearing technology also called Visikol® that can render biological tissues transparent so that they can be imaged in 3D instead of the traditional 2D approach. Visikol is focused on developing easy-to-use tissue clearing reagents and kits and has launched their Visikol® HISTO™ platform so that any researcher can add a new dimension to their research.

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Virtual Reality Walk Through of Mouse Brain Vasculature



Visikol HISTO - Owl Brain



Adopt tissue clearing into your research quickly and easily.

They have developed Visikol® HISTO™ as the first commercially available, easy-to-use, non-destructive and rapid 3D histology platform. With Visikol HISTO you are able to visualize biological tissues in 3D by pairing the rapid clearing of Visikol HISTO with fluorescent labeling. 

Benefits of Visikol HISTO

  • Rapid tissue clearing
  • Easy-to-use
  • No special equipment required
  • Compatible with IF, FP and other fluorescent labels
  • Affordable for all researchers
  • Customized protocols for all applications
  • Reversible for follow up 2D H&E/IHC
  • Non-destructive to morphology

Why Visikol HISTO for tissue clearing? 

There are several tissue clearing techniques that have been developed over the last few years each of which have unique advantages and disadvantages. However, the adoption of tissue clearing into research as a reliable tool for bio-imaging has been rather limited, as each technique requires specific adaptations for differing tissue types, labels, fixation methods, imaging modalities and custom microscope objectives.

Visikol Inc. has developed the Visikol HISTO technology in collaboration with over 400 research labs across the US and EU, and have built the Visikol HISTO Protocol Guidebook to ensure that tissue clearing is easy to adopt for all applications. Visikol HISTO is easy-to-use, rapid, and affordable. Furthermore, Visikol HISTO provides reversible clearing, which means that 3D data can be validated against traditional histology.

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