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Proteins and Peptides

1,10 phenanthroline

Product Sizes
50 mg
£257.00
SI-9649-0500-50MG
About this Product
SKU:
SI-9649-0500
Application:
Cell-based/Functional Assay
Extra Details:
1,10-phenanthroline (o-phenanthroline) is a chelator with a high affinity for divalent metal ions. While not specific for DUBs, it has been shown to be a potent inhibitor of JAMM-type isopeptidases through chelation of the active site Zn2+ ion. As such, o-phenanthroline is widely used when preparing cell lysates for the enrichment of proteins bearing K63-linked polyubiquitin chains which are especially sensitive to DUBs in the JAMM family.
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Supplier:
LifeSensors
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors