Peptides
Peptide Overview
Peptides, short chains of amino acids, are pivotal in research due to their multifaceted roles. They serve as vital signalling molecules, with peptide-based hormones like endorphins regulating diverse physiological processes. Some peptides function as enzymatic catalysts, such as ribonuclease, participating in biochemical reactions. In terms of structural support, peptides contribute to the integrity of crucial biological molecules like collagen, the foundation of skin, bones, and connective tissues. Additionally, peptides play a significant role in immune function, with certain peptides acting as antigens to stimulate immune responses and defences against pathoge
Peptide Research Applications | ||
Solid-Phase Peptide Synthesis (SPPS) | Mass Spectrometry (MS) | Nuclear Magnetic Resonance (NMR) Spectroscopy |
SPPS is a method to create custom peptides and investigate their structure and function. | Peptides are analysed using MS to determine their sequences and post-translational modifications. | NMR is used to study the three-dimensional structure and dynamics of peptides. |
Fluorescence Resonance Energy Transfer (FRET) | Cellular Imaging | Peptide Arrays |
FRET is used to investigate protein-protein interactions and conformational changes, often with fluorescently labelled peptides or proteins. | Peptides can be labelled with fluorophores for cellular imaging using techniques like confocal microscopy and super-resolution microscopy. | These arrays are used to simultaneously screen large numbers of peptides for interactions with proteins, antibodies, or other molecules. |
Peptides are remarkably versatile molecules that play a crucial role in both research and practical applications across a spectrum of scientific and medical fields. They are fundamental in drug development, serving as the basis for pharmaceuticals like insulin, antiviral agents, and cancer treatments due to their specificity and low toxicity. Peptides are pivotal in vaccine design, where they stimulate targeted immune responses against infectious agents. Furthermore, in hormone replacement therapies, peptides like growth hormone are instrumental.
In biotechnology, peptides act as molecular tools for protein research and purification. Their role extends to tissue repair, as they are integral to extracellular matrix proteins, contributing to wound healing and regenerative medicine. Peptides are additionally crucial in diagnostic assays, allowing for sensitive biomarker detection.
In addition to these practical applications, peptides are indispensable tools in various research disciplines, including biochemistry, pharmacology, immunology, neuroscience, and analytical chemistry, facilitating the investigation of protein function, immune responses, and structural biology. This adaptability and versatility underscore the profound impact of peptides in both scientific exploration and healthcare solutions.
Peptides from 2BScientific | |||||
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2BScientific not only prides itself on its services, but in doing so we ensure that our suppliers are something to be proud of also! That’s why we have partnered with Isca Biochemicals, SB-Peptide, Jena Bioscience, Alpha Diagnostic, Cusabio, AltaBiosciences, Echelon Biosciences and Synaptic Systems to ensure we can provide our customers with the most cutting edge, reliable and accurate peptides and relevant peptide related reagents.