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Antibodies

CD3 PE-Cyanine 5

Product Sizes
25 tests
£252.00
105374-25TESTS
About this Product
SKU:
105374
Application:
Flow Cytometry
Clone:
UCHT1
Clonality:
Monoclonal
Conjugate:
R-PE-Cyanine 5
Extra Details:
The monoclonal UCHT1 clone recognizes CD3E Epsilon antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3G Gamma chain, a CD3D Delta chain, and two CD3E Epsilon chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the Z Zeta-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3E Epsilon is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.
Host:
Mouse
Purity:
>95%
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
2-8[o]C
Supplier:
Caprico Biotechnologies
Type:
Antibody: Monoclonal Antibody