- Apoptosis
Apoptosis
Cell death is a fundamental aspect of the life cycle of the eukaryotic cell. Homeostasis implies a balance between cell proliferation and cell death, and this balance is essential for the development and maintenance of multicellular organisms. Dysregulation of either cell death or proliferation leads to a wide range of pathologies including cancer, neurodegenerative disease, and aberrant embryogenesis. In contrast to necrosis, which is a form of traumatic cell death that results from acute cellular injury, apoptosis, in general, confers advantages during an organism's life cycle. For example, the differentiation of fingers and toes in a developing human embryo occurs because cells between the fingers apoptose; the result is that the digits are separate. Between 50 and 70 billion cells die each day due to apoptosis in the average human adult. These mechanisms act in series or in parallel, each of which can be variably expressed in different eukaryotic species and within the same species, among distinct cell types.
Resources
See the amazing Apoptosis video
*Special Offers |
25% Discount across all of IMGENEX Apoptosis Range - including the New pSIVA (the first reversible apoptosis probe for detecting phosphatidylserine (PS) exposure on plasma membranes) |
| 30% Discount on the NEW MitoPT™ Kits - assess changes in mitochondrial membrane potential and detect mitochondrial depolarization |
[*Please contact us for terms & conditions of offer]
Products
 |
Assay Kits | A wides selection of in vitro & in vivo assays kits to detect Apoptosis. These include: |
|
 |
Antibodies | Rabbit Polyclonals | |
 |
Proteases | Human Caspase & Protease | |
 |
Cellular Dyes |
Resources
See the amazing Apoptosis video
We are dedicated to providing the best reagents and service in the UK. Please leave your contact details and inquiry here and we will get back within 24 hours.
